Lazio-Roma will take place at 02:45 PM (EST) on April 15, 2018, at the Stadio Olimpico.
Roma faces Lazio in the Derby della Capitale after the Champions League hangover. Both teams are competing for a Champions League spot.
Di Francesco should confirm the new tactical approach used to defeat Barcelona on Tuesday. His 3-4-3 or 3-4-1-2 should be played with the fast Juan Jesus. The Brazilian will help Manolas and Fazio in the backline.
De Rossi is the playmaker. Peres and Kolarov should be the fullbacks while Strootman should operate in midfield to help the Roma captain.
Dzeko is the striker with Schick very close to the Bosnian star. Nainggolan could play right behind them or slightly on the right offensive flank.
Lazio-Roma: Probable Lineups (Serie A 2017-18)
Lazio (3-5-1-1): Strakosha; Bastos, Wallace, Radu; Marusic, Parolo, Lucas Leiva, Lulic; Milinkovic-Savic, Luis Alberto; Immobile.
Roma (3-4-3): Alisson; Fazio, Manolas, Juan Jesus; Bruno Peres, De Rossi, Strootman, Kolarov; Schick, Dzeko, Nainggolan.
Coach: Di Francesco